Paul Villoutreix

Embryogenesis is a fascinating process. It is the process by which a single fertilized cell is turned into a multi-cellular organism. It is a really beautiful phenomenon, studied in various species, from the sea urchin, to the fruit fly, to the zebrafish, to the chicken, to the mouse, to the human.

Recent technological developments in microscopy imaging techniques have transformed embryology into a data intensive science. As an interdisciplinary scientist, I am interested in topics at the intersection of developmental biology, mathematics and data visualization. Currently, I am a postdoc at the Weizmann Institute of Science in Rehovot (Israel) working in Eli Zelzer’s lab and a visiting fellow of the Center for Data Arts at the New School in New York. Previously, I was a postdoc in Stas Shvartsman’s lab at Princeton University

In addition, I am leading the open science project the Embryo Digital Atlas: a logoweb based platform for the visualization of complex experimental datasets of embryogenesis in an easy and beautiful way. You can contribute here.

We are now extending the interactive visualization tool to Virtual Reality headsets, thanks to a mini grant award by the Mozilla Science Lab. All the code is developed openly and hosted on this github repository.

Recent news: I will be presenting our work at the 2018 NEUBIAS Conference in Szeged, Hungary.

Twitter: @paulvilloutreix

Publications

Google Scholar Citations

Journals

Multiscale analysis of 3D nuclear morphology reveals new insights into growth plate organization in mice
Sarah Rubin*, Tomer Stern*, Paul Villoutreix, Johannes Stegmaier, Yoseph Addadi, Elazar Zelzer – submitted

Entropy effects in cell lineage tree packings
Jasmin Imran Alsous*, Paul Villoutreix*, Norbert Stoop*, Stanislav Y. Shvartsman, Jörn Dunkel – Nature Physics, DOI:10.1038/s41567-018-0202-0imranalsous_naturefigure2

News & Views
Connected development
Ben D. MacArthur, Nature Physics, 2018

Featured in Nature (with Jasmin Imran Alsous):
The visualizations transforming biology
Ewan Callaway, Nature, 535(7610), 187-188, 2016.

Synthesizing developmental trajectories
Paul Villoutreix*, Joakim Andén*, Bomyi Lim, Hang Lu, Yannis Kevrekidis, Amit Singer, Stanislav Y. Shvartsman – PLoS Comput Biol 13(9): e1005742, 2017.

Cover of September’s issue of PLoS Computational Biology

Collective Growth in a Simple Cell Network
Jasmin Imran Alsous, Paul Villoutreix, Alexander M. Berezhkovskii, Stanislav Y. Shvartsman – Current Biology 27(17), 2670–2676, 2017.

A post by Jasmin Imran Alsous featured on The Node describing the story behind the paper “Collective Growth in a Simple Cell Network”
Allometry in a Simple Cell Network – The Node, 2017.

screen-shot-2017-02-17-at-6-47-51-pmAn integrated modelling framework from cells to organism based on a cohort of digital embryos
Paul Villoutreix*, Julien Delile*, Barbara Rizzi*, Louise Duloquin*, Thierry Savy, Paul Bourgine, René Doursat, Nadine Peyriéras, Scientific Reports, 6:37438, 2016.
Code and Datasets or github repository

Book Chapter

Vers une modélisation multi-échelle de la variabilité biologique?
Paul Villoutreix, Chap. 19 in Modéliser & Simuler. Epistémologies et pratiques de la modélisation et de la simulation. Tome 2, Franck Varenne, Marc Silberstein, Philippe Huneman et Sebastien Dutreuil, Eds. pp. 643 – 664, Editions matériologiques, Novembre 2014.

Ph.D Thesis

rplot_allred_eyeyellowRandomness and variability in animal embryogenesis, a multi-scale approach
Paul Villoutreix, PhD Dissertation – Université René Descartes – Paris V, 2015

Others

Piece of news on the Embryo Project Encyclopedia.

Showcase on the Information is Beautiful Award website.

Picture1Blog post describing The Embryo Digital Atlas’ journey to the Global Sprint.

Interview on Mozilla Science Lab blog – The Embryo Digital Atlas.

@mozillascienceBlog post discussing our work on data-driven visualizations of developing embryos and its relationships to art. This is a supporting webpage for Mozilla Science Lab  community call on art and science.

Research Positions

2017 – Present | Postdoctoral Fellow – Zelzer Lab – Weizmann Institute of Science
2017 – Present | Visiting Fellow – Center for Data Arts – The New School, NYC
2015 – 2017 | Postdoctoral Fellow – Shvartsman Lab – Princeton University

Education

CV

2015 | PhD in Mathematical Biology
Paris Descartes University – Frontiers of Life Science Program
2014 | Visiting Student Researcher
Stanford University – Department of Mathematics
2011 | MSc. Interdisciplinary Approaches of Life Sciences
Paris Diderot University
2011 | MSc. Applied Mathematics
Supélec Engineering School

Contact

paul.villoutreix@weizmann.ac.il
Department of Molecular Genetics
Weizmann Institute of Science
Rehovot, Israel

villoutp@newschool.edu
Center for Data Arts
The New School
2 West 13th Street RM 1011
New York, NY, 10011

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